Complete joint support formula.
Joint Armor is scientifically formulated to provide the four most essential elements for joint health: glucosamine, chondroitin sulfate, hyaluronic acid, and manganese sulfate. While other products include one or two of these ingredients, Joint Armor provides all four elements at therapeutic levels, all for the price of one supplement.
Joint Armor includes:
Per 7 g scoop
Glucosamine HCl …………………2,500 mg
Glucosamine sulfate ……………2,500 mg
Chondroitin sulfate ……………..1,200 mg
Hyaluronic acid ……………………..100 mg
Manganese sulfate ………………..100 mg
Glucosamine and Chondroitin Sulfate
Glucosamine and chondroitin sulfate are key nutrients necessary for maintenance of normal joint function. Glucosamine is used as a substrate for certain components of the cartilage matrix, while chondroitin sulfate plays an important role in controlling the enzymes associated with inflammation and tissue destruction. Numerous studies have documented the benefits of combining these two ingredients to joint health.
Studies using equine cartilage explants (small pieces of actual living tissue) have shown these ingredients complement each other in inhibiting the production of inflammatory cells. Interestingly, when these ingredients were used independently of each other, they did not show similar benefits (Orth et al., 2002; Schlueter and Orth, 2004; DeChant et al., 2005).
Glucosamine and chondroitin sulfate have been evaluated in several field studies. In a double-blind placebo-controlled study (Hanson et al., 2001), 14 horses with progressive forelimb lameness showed significant improvement (evaluated by lameness specialists using standardized lameness scores) when administered a treatment of glucosamine and chondroitin for a 28-day treatment period when compared with the control group. In a more recent study (Rodgers, 2006), administration of glucosamine and chondroitin significantly decreased the necessity and frequency of intra-articular therapeutic injections of the hock joints in working show hunters and jumpers.
Hyaluronic acid (HA) is an integral component of synovial fluid and articular cartilage, and is responsible for lubrication of the joint surfaces. While glucosamine and chondroitin sulfate work mainly on the cartilage, HA is more beneficial to the joint fluid. In a study conducted by Bergin and coworkers (2006), oral HA was effective in reducing synovial effusion (an abnormal collection of fluid) following arthroscopic surgery for removal of osteochondritis dissecans (OCD) lesions in joints.
Manganese is an important cofactor in the formation of the cartilage matrix and synthesis of connective tissue.
Bergin, B.J., Pierce, S.W., Bramlage, L.R. & Stromberg, A. (2006). Oral hyaluronan gel reduces post-operative tarsocrural effusion in the yearling Thoroughbred. Equine Veterinary Journal, 38 (4), 375-378.
DeChant, J.E., Baxter, G.M., Frisbie, D.D., Trotter, G.W. & McIlwraith, C.W. (2005). Effects of glucosamine hydrochloride and chondroitin sulfate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism. Equine Veterinary Journal, 37 (3), 227-231.
Hanson, R.R., Hammad, T.A. & Brawner, W.R. (2001). Oral treatment with a nutraceutical (Cosequin) for ameliorating signs of navicular syndrome in horses. Veterinary Therapeutics, 2 (2), 148-159.
Orth, M.W., Peters, T.L. & Hawkins, J.N. (2002). Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulfate. Equine Veterinary Journal, 34, 224-229.
Rodgers, M.R. (2006). Effects of oral glucosamine and chondroitin sulfates supplementation on frequency of intra-articular therapy of the horse tarsus. Intern. J. Appl. Res. Vet. Med. 4 (2), 155-161.
Schlueter, A.E., & Orth, M.W. (2004). Further studies on the ability of glucosamine and chondroitin sulfate to regulate catabolic mediators in vitro. Equine Veterinary Journal. 36 (7), 634-636.