Building a Strong Immune System in Mares and Foals
Natural vitamin E supplementation of broodmares during late gestation and early lactation can give foals a leg up in building a strong immune system. Researchers have recently investigated the value of vitamin E in mares. When supplemented with vitamin E, mares show increased passive transfer of antibodies to foals, which ensures the strength of the neonatal immune system. Foals that do not consume enough colostrum or receive only poor-quality colostrum often have failure of passive transfer (FPT), where an inadequate immunoglobulin intake can lead to illness and death.
In one study, pregnant mares were supplemented with 2,500 IU of water-soluble, natural vitamin E from the last month of pregnancy into the first few days of lactation. Bondo and Jensen (2010) reported mares supplemented with the water-soluble, natural vitamin E had higher levels of vitamin E, IgG and IgM in their colostrums and milk. Subsequently, higher blood levels of IgM and vitamin E were reported in the foals of the supplemented mares.
Providing natural vitamin E to pregnant mares will support healthy transfer of antibodies from mare to foal.
Source matters.
Natural vs. synthetic vitamin E
There are physiological differences in the absorption, utilization, and tissue retention between synthetic and natural vitamin E. In fact, the body preferentially transports and incorporates natural vitamin E into tissues. Current research in several species, including horses, shows that natural vitamin E is two to three times more potent than synthetic.
Many feeds and supplements contain synthetic vitamin E which is noted in the ingredient list as dl-alpha-tocopherol or “vitamin E supplement.” When supplementing with vitamin E, be sure you choose a natural vitamin. When reviewing the ingredient listing on your feed or supplement, look for the little “d” in front of the name: d-alpha-tocopherol. It may be written out as “natural vitamin E.”
Kentucky Performance Products, LLC offers two natural vitamin E products to choose from: Elevate® W.S. and Elevate® Maintenance Powder.
Elevate W.S., a water-soluble liquid, effectively crosses the blood – brain barrier to support a horse’s central nervous system. Research-proven to deliver a highly bioavailable source of natural vitamin E, Elevate W.S. begins raising blood vitamin E levels within 3 days.
Recommended Use Rates of Elevate W.S.
- Maintenance: 1,000 IU/day
- Stalled horses or horses maintained on poor pasture: 1,000-2,000 IU/day
- Intense training: 3,000 IU/day
- Pregnant and lactating mares: 3,000 IU/day
- Foals: 3,000 IU/day
Elevate Maintenance Powder was developed to provide a highly bioavailable source of natural vitamin E in an easy-to-feed form for long-term supplementation. As with water-soluble vitamin E, it supports a strong immune system in mare and foals. Elevate Maintenance Powder begins to raise vitamin E levels in the blood in a matter of weeks. Choose Elevate Maintenance Powder as a follow-up to Elevate W.S. or when a slow, steady increase in vitamin E levels is appropriate.
Recommended Use Rates of Elevate Maintenance Powder
- Maintenance: 1-2 scoops per day (1,000-2,000 IU vitamin E per day)
- Intense training: 3-5 scoops per day (3,000-5,000 IU vitamin E per day)
- Pregnant/lactating mares: 3 scoops per day (3,000 IU vitamin E per day)
- Foals: 3 scoops per day (3,000 IU vitamin E per day)
- Stallions: 3 scoops per day (3,000 IU vitamin E per day)
- Neurological challenges: Consult your treating veterinarian


2 Comments
I have a mare that will not get in foal with a baby on her side. She cycles and ovulates But will not get preg. If you wait the year and breed her 1st heat cycle gets in foal no issues. Any suggestions
We’re sorry to hear that you’re struggling with your mare’s reproductive health. We always suggest that you speak to your veterinarian about your horse’s specific health issues. In terms of supplements, there is increasing evidence that vitamin E supplementation may increase fertility in mares. Due to modern management practices, mares may not be receiving adequate vitamin E nutrition through rations composed solely of hay and grain. Supplementation will increase circulating levels of vitamin E and may positively affect fertility. We generally recommend beginning supplementation prior to the breeding season with 2,500 to 5,000 IU of Elevate® vitamin E and continuing throughout the gestation and lactation period. We would suggest combining the Elevate natural vitamin E with Contribute™ for a mare like this. A supplemental source of omega-3 fatty acids, Contribute supports the reduction of lingering inflammation, while vitamin E supports the immune system. We recommend discussing these supplements with your veterinarian. – Veronica, Kentucky Performance Products