Influence of Source and Quantity of Supplemental Vitamin E on Equine Serum and Cerebrospinal Fluid a-Tocopherol and Its Implication for Neurologic Diseases


Two studies were conducted at the University of California, Davis to measure effects of vitamin E supplementation on serum and cerebrospinal fluid (CSF) α-tocopherol levels.

The first study was conducted to determine if there were differences in serum and CSF α-tocopherol levels between two groups of horses supplemented with two levels of vitamin E as water-soluble natural d-alpha-tocopherol. These results showed that daily administration of 10,000 IU of vitamin E, as water -soluble d-α-tocopherol, was able to cross the blood-brain barrier in healthy horses. This allowed for vitamin E to reach the target site, the brain and spinal cord, and be potentially beneficial for horses with neurologic disease.

The second study was conducted to determine if there were differences in plasma and CSF α-tocopherol levels when horses were supplemented with natural versus synthetic vitamin E. It was concluded that vitamin E supplemented as water-soluble natural d-alpha-tocopherol was transferred across the blood-brain barrier more effectively than an equal IU quantity of synthetic vitamin E.

Read the full article here.


Article written by Ed Kane, PhD; Robert L. Stuart, PhD; and Nicola Pusterla, DMV, DMV Habil

Copyright (C) 2012 Kentucky Performance Products, LLC.   All rights reserved.

Article sponsored by Elevate W.S.; fast-acting, water-soluble, natural vitamin E, a powerful antioxidant when you need to raise blood tocopherol (vitamin E) levels quickly, or when high dose administration is required.

When health issues arise, always seek the advice of a licensed veterinarian who can help you choose the correct course of action for your horse. Supplements are intended to maintain healthy systems and support recovery and healing. They are not intended to treat or cure illness or injury.

About Kentucky Performance Products, LLC:

Since 1998, Kentucky Performance Products has simplified a horse owner’s search for research-proven nutritional horse supplements that meet the challenges facing modern horses. KPP horse supplements target specific nutritional needs and are formulated to complement today’s feeds, thus safeguarding against over-supplementation. Each product is scientifically formulated and made with high-quality ingredients at certified manufacturing facilities. Kentucky Performance Products is proud to offer a quality assurance promise backed by a money-back guarantee. Kentucky Performance Products brings you horse supplements you can count on because the horse that matters to you, matters to us.

Category : Essential Vitamins | Tips and Topics

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