What Is the Difference Between Neigh-lox Original and Neigh-lox Advanced?

The original Neigh-Lox®, with the blue label, was developed in 1996 to address the ever-growing problem of stomach ulcers in horses. Neigh-Lox’s proprietary formula maintains normal stomach pH by buffering excess gastric acid and coating the stomach. Four ounces (2 scoops) of Neigh-Lox helps maintain normal stomach pH for 6 to 8 hours. Neigh-Lox can be offered two to three times daily to horses that are at high risk for developing ulcers due to pervious history or current lifestyle. Neigh-Lox can be used as needed during times of stress to maintain a healthy stomach. Neigh-Lox is an excellent follow-up to a course of omeprazole to support continuing recovery.

Neigh-Lox® Advanced, with the pink label, was formulated in response to growing concerns related to the poor hindgut health experienced by many modern horses. Diets rich in starch and stressful lifestyles make modern horses susceptible to gastric ulcers, colonic ulcers, hindgut acidosis, and microbial imbalances leading to colic, diarrhea, and laminitis. Neigh-Lox Advanced contains ingredients that not only buffer and coat the stomach like original Neigh-Lox, but support healing and lower levels of inflammation throughout the digestive tract. Neigh-Lox Advanced has yeast fermentation metabolites that support the reduction of pathogenic bacteria while populating the gut with beneficial bacteria. The inclusion of saccharomyces boulardii in Neigh-Lox Advanced reduces the risk of hindgut imbalances by supporting complete digestion of starches and sugars in the foregut, before they can escape into the hindgut and cause problems. Additionally, S. boulardii supplies nutrients to the gastrointestinal tissues that support the growth of healthy cells and healing of damaged tissue. Daily supplementation of four ounces (2 scoops), two to three times per day of Neigh-Lox Advanced is recommended. Continual support is the key to recovery and maintenance of a healthy digestive tract.



  • Hi Sarah,

    Actually Neigh-Lox Advanced contains several ingredients that make it unique and different than common probiotics or digestive aids. It contains a proprietary blend of yeast fermentation metabolites that contribute to the gut in multiple ways. They support the growth and activity of a beneficial microbial population (much like a probiotic), but they also supply antioxidants, polyphenols, nucleotides and polysterols to the tissues themselves that stimulate the immune response and support reduced inflammation. Neigh-Lox Advanced contains saccharomyces boulardii which supports improved starch and sugar digestibility in the foregut, so less of these easily fermentable carbohydrates escape into the hindgut where they can cause problems. Research has shown that S. Boulardii supports the healing of GI tract tissues. It is this multi-prong approach to total digestive tract support that makes Neigh-Lox Advanced different.

  • So basically the pink has added a probiotic?

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